DESCRIPTION
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Poke root (Phytolacca americana) is a flowering shrub with red-pink stems and black-purple berries. It’s native to the southwest and eastern regions of the United States. You can also find it in South America, Europe, and Asia.
Sometimes, it’s grown for culinary or decorative purposes.
Poke root has many names, including:
pokeweed
pokeberry
inkberry
American nightshade
American scoke
pigeonberry
red plant
pocan
Historically, people have used poke root in food, herbal medicine, and dye for fabric and wine. However, despite these traditional uses, the whole plant is toxic to people. It needs to be cooked in a specific way to reduce its toxicity or have its beneficial compounds extracted from it in a lab. Experts recommend not consuming poke root or any part of the pokeweed plant.
Let’s explore what the science says about poke root, its side effects, and its uses.
Can poke root fight cancer?
Researchers have studied specific compounds of the pokeweed plant, including the roots, by isolating them in a lab.
According to a 2023 researchTrusted Source, earlier test tube studies demonstrate that, when extracted from the plant, some of these bioactive compounds may have anticancer and antifungal effects:
Breast cancer: The authors suggest that one of these compounds, Esculentoside A, may inhibit breast cancer growth, while another, Esculentoside H, may prevent human cancer cells from migrating.
Colon cancer: The authors also refer to earlier research that suggests compounds isolated from pokeweed seeds, americanin A and isoamericanol A, may have anticancer effects on colon and breast cancer.
Additionally, the 2023 researchers experimented with cultivating poke root to increase these beneficial compounds in this study and an earlier 2022 studyTrusted Source. Their results suggest that pokeweed roots cultivated under specific conditions in a lab may contain more of these properties than poke roots cultivated in the wild or those sold as herbal supplements.
Additional research on pokeweed and its possible cancer-fighting compounds is still needed. How a compound acts in a test tube or animal study does not always predict how it will act in the human body, which is much more complex.
New research is still needed to examine:
poke root’s possible anticancer effects
how its effectiveness may compare to current treatments
if effective, whether the benefits extend to humans
what kind of dosage may be safe and effective (www.healthonline.com)
